Leukaemia and reproductive outcome among nurses handling antineoplastic drugs.

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Leukaemia and reproductive outcome among nurses handling antineoplastic drugs.

During the past decades conclusive evidence has accumulated that alkylating antineoplastic drugs (ADs) can cause cancer, most notably acute non-lymphocytic leukaemia, and that most ADs are reprotoxic. Studies on health workers handling ADs have shown significantly increased risks for miscarriages (two studies) and malformations (two studies). The present study monitored the risk for cancer and ...

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a cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). the control group, matched by sex, and age, consisted of 18 nurses, worked on other sect...

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"sister chromatid exchanges and micronuclei in lymphocyte of nurses handling antineoplastic drugs"

individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. the effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different university hospitals in shiraz (iran) and in a group of 18 unexposed nurses as control group. the cytogenetic repercussions of exposure were asses...

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knowledge, attitude, and performance of oncology nurses handling antineoplastic drugs in hospitals of urmia university, iran

original article   introduction: antineoplastic drugs (ands) for the treatment of cancers could result in occupational exposure of nurses and consequent side effects. this study aimed to evaluate knowledge, attitude, and performance of oncology nurses and to survey nurses’ chemotherapy workload and the experienced side effects. method: a cross-sectional study was conducted at four hospitals of ...

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Determination of Urinary Cyclophosphamide in Oncology Nurses Handling Antineoplastic Drugs by Gas Chromatography-Mass Spectrometry

125 Determination of Urinary Cyclophosphamide in Oncology Nurses Handling Antineoplastic Drugs by Gas Chromatography-Mass Spectrometry Summary : The aim of the study was to detect exposure to antineoplastic drugs, using cyclophosphamide (CP) as the model compound, in nurses who worked in oncology departments of hospitals. Chemotherapy with antineoplastic agents is often used in the treatment of...

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ژورنال

عنوان ژورنال: Occupational and Environmental Medicine

سال: 1992

ISSN: 1351-0711

DOI: 10.1136/oem.49.12.855